LIFECODES Transfusion Medicine by Immucor
?Platelets represent a critical component of the body’s clotting function and are one of the most commonly transfused of all blood components. Correct determination of platelet type and the presence of antibody to platelet antigens as a bar to platelet transfusion, provides important information to clinicians and transfusion professionals. With the addition of platelet antibody and platelet typing assays to Immucor’s product portfolio, we continue our mission to provide the best-in-class products that will lead to transfusions that are safe, accessible and affordable.
Antibody Detection Products
?LIFECODES MACE1 provides a well-characterized monoclonal antibody immobilized in the microwells which are used to capture the glycoproteins from platelets supplied by the user. This product allows a user to detect and differentiate between antibodies that bind to the platelet-specific glycoproteins. MACE kit provides tests that can be used for either antibody identification (if previously-typed platelets are utilized) or a platelet crossmatch (if potential donor platelets are utilized). 1
- Discriminates anti-platelet and anti-HLA donor/recipient reactions
- Cross-match results aid in selection of appropriate platelet units
- Identifies donor-specific anti-platelet antibodies
1 LIFECODES Mace1 for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
Platelets express glycoproteins that are polymorphic and can become the targets for antibody responses. Detecting these antibodies offers the clinician the potential to better identify compatible blood products and improve patient care.
LIFECODES Pak Family ELISA Products
The Pak family of products provide well-characterized platelet glycoproteins immobilized either directly and/or captured by monoclonal antibodies to the wells of a microwell plate. The available formats allow a user to detect antibodies that bind to the platelet-specific glycoproteins (IIb/IIIa, Ib/IX, Ia/IIa and IV) and Class I HLA. 1,2,3,4
PakAuto has been designed to detect autoantibodies to patient glycoproteins. These antibodies are eluted from the patient’s own platelets or found circulating in plasma. 5
- Kits available for both allo and auto platelet antibody detection
- Differentiate HLA from platelet antibodies
- Multiple kit formats allow for maximum flexibility
1 LIFECODES PakPlus for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
2 LIFECODES Pak12 for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
3 LIFECODES Pak12G for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
4 LIFECODES Pak2-LE for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
5 LIFECODES PakAuto for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
?Donor Screening
The presence of pre-existing HLA antibodies in blood donors has been implicated in Transfusion-Related Acute Lung Injury (TRALI) and TRALI-like transfusion reactions in the recipients of blood products from sensitized donors. TRALI is a syndrome that is described as a spectrum of clinical symptoms that occur very rapidly (usually in 1-2 hours) following transfusion with blood products. Occurring in a small number of patients that receive blood products, it remains the leading cause of transfusion-related deaths reported to the Food and Drug Administration.
Screening for HLA antibodies has now been made available to the Blood Bank lab in one convenient kit called LIFECODES DonorScreen-HLA. DonorScreen-HLA has been specifically designed to detect these antibodies in blood donors using the QuickStep automated ELISA processing instrument. 1
- QuickStep automation allows screening of 176 donor samples for both Class I and Class II HLA antibodies in a single run
- Most kit reagents are ready-to-use and can be directly placed on the instrument
- Automation provides walk-away use
- Can use donor samples stored for up to 96 hours at room temperature in primary collection tube
- Can use either plasma or sera
- System accepts eight (8) barcodes at one time, including: Code 128, Code 39, Pharmacode, Codabar
- Barcoded reagent bottles eliminate set-up mistakes
- Barcode reading of donor sample tubes provides data traceability
1 LIFECODES DonorScreen-HLA for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
?HPA Genotyping
LIFECODES ThromboType Products
?
The Human Platelet antigens (HPAs) can be targets for alloimmune and autoimmune antibody responses that cause life-threatening bleeding disorders, such as refractoriness to platelet transfusions, post-transfusion purpura and neonatal alloimmune thrombocytopenia.
LIFECODES ThromboType and ThromboType1 are replacements for platelet serological testing and adjuncts to HLA matching in selecting compatible platelets for alloimmunized recipients. ThromboType contains the reagents necessary to identify an individual’s genotype for HPA-1, 2, 3, 4, 5, 6 and 15, using a gel endpoint. ThromboType1 contains the reagents necessary to identify an individual’s genotype for HPA-1 using a gel endpoint. 1,2
- Less than 100 minutes from DNA to results
- Bufferless pre-cast gels included
- Comprehensive typing of the most common HPA alleles
1 LIFECODES ThromboType for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
2 LIFECODES ThromboType1 for in vitro diagnostic use [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
?Red Cell Genotyping
The LIFECODES RBC and LIFECODES RBC-R products 1 utilize Luminex technology in two multiplex assays for the genotyping of red blood cell (RBC) antigen blood groups. The LIFECODES RBC assay consists of highly prevalent single nucleotide polymorphisms (SNPs) of 6 blood antigen groups. The LIFECODES RBC-R assay consists of rare SNPs of 9 blood antigen groups.
LIFECODES RBC assay
The LIFECODES RBC assay uses single nucleotide polymorphism (SNP) detection by the Polymerase Chain Reaction – Reverse Sequence Specific Oligonucleotide (PCR-RSSO) method. This multiplex assay has been optimized to genotype for the antigens of the following highly prevalent blood groups:
- Kell – K, k, Kpa, Kpb, Kpc, Jsa, Jsb
- Kidd – Jka, Jkb, Jk (Finnish null)
- Duffy – Fya, Fyb, Fyx (a-b weak), FyGATAsil
- MNS – M, N, S, s, S-s-Uvar (includes 2 S silencing mutations: – GPB230 and GPB intron +5)
- Rh – C, c, E, e
- Dombrock – Doa, Dob
LIFECODES RBC-R assay
The LIFECODES RBC-R assay uses single nucleotide polymorphism (SNP) detection by the Polymerase Chain Reaction – Reverse Sequence Specific Oligonucleotide (PCR-RSSO) method. This multiplex assay has been optimized to genotype for the antigens of the following rare blood groups:
- Colton – Coa, Cob
- Dombrock – Hy, Joa, Doa, Dob
- Scianna – Sc1, Sc2
- Lutheran – Lua, Lub
- Diego – Dia, Dib, Wra, Wrb
- Landsteiner-Wiener – LWa, LWb
- Cartwright – Yta, Ytb
- Knops – Kna, Knb, McCa+, McCb+, SI1, SI2
- Cromer – Cra
1 LIFECODES RBC Genotyping for research use only [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.
LIFECODES Red Cell EZ Type uses allele-specific PCR amplification, with primer sets dried in PCR tubes to resolve incompatibilities that are difficult or impossible to identify by serologic methods.
Bufferless, pre-cast agarose gels (the EZ Type format), improve workflow by eliminating buffer preparation; gel-casting and the wait for gel hardening. A wide selection of kits is available to type for only the specific blood group system(s) needed.
- Flexible: Choose only the alleles you want to type
- Convenient: Utilizes pre-cast, bufferless gels
- Reliable: Established and trusted technology.
McFarland Standards from Pro-Lab Diagnostics
The McFarland Standards are intended for adjusting densities of bacterial suspensions. All standards are supplied in protective carrying cases and have a shelf life of up to two years from the date of manufacture.
Seracult® Fecal Occult Blood Tests by Propper Manufacturing
A collection of qualitative solutions for the diagnosis of colorectal cancer. Simply apply a stool sample to one side of guaiac-impregnated paper, and apply two drops of developer to the other side. The result will produce a blue color if the stool sample contains occult blood.
Results are ready in 30–60 seconds.
Triple slides are for use with stool samples from three bowel movements, while single slides are for used when an immediate evaluation and diagnosis is needed from a single bowel movement or rectal exam.
- Seracult Single Slides: 100 slides.
- Product #: CATLA-371001
- 100 slides, two 15 ml bottles of developer and 100 applicators
- Seracult Single Slides: 1000 slides.
- Product #: CATLA-371002
- 1000 slides, two 15 ml bottles of developer and 1000 applicators
- Seracult Single Slides: 1000 slides 371002SP
- Product #: CATLA-371002
- 100 slides
- Seracult Patient Kit
- Product #: CATLA-372003
- Two boxes, each containing 50 kits (triple slide and 3 applicators in dispensing envelope) and three 15 ml bottles of developer Case of 100
- Seracult Triple Slides
- Product #: CATLA-372004
- 34 triples slides, two 15 ml bottles of developer and 102 applicators Box of 34
- Seracult Triple slides
- Product #: CATLA-372005
- 340 slides, twenty 15 ml bottles of developer and 1020 applicators
- Seracult Mailing Kit
- Product #: CATLA-372007
- Two boxes, each containing 40 kits (triple slide & 3 applicators, 3 collection tissues and USPS approved foil lined mailing envelope) and two 15 ml bottles of developer Case of 80
- Seracult Tape Kit
- Product #: 379010
- Two kits, each containing one roll of tape (for 100 tests) and one 15 ml bottle of developer
- Seracult Developer, 15 mL
- Product #: 379015
- 20 bottles, 15 ml each Box of 20
- Seracult Mailing Pouches
- Product #: 379016
- 100 Seracult Primary Envelopes with patient instructions Box of 100
Controls and Assay systems from Quantimetrix
Dipper® Urine Dipstick Control
- Simulates patient testing
- Liquid, made with human urine
- 18-month refrigerated shelf life from date of manufacture
- 3 months (or 20 dips) open vial stability when stored at 2 – 8º C*
Dipper Urine Dipstick Control lets you monitor the performance of visual and instrumental readings of urine dipsticks by immersing the dipstick into the control – the same way you test your patient samples. We include values for all dipstick analytes plus microalbumin and creatinine, and qualitative results for hCG early pregnancy detection test methods. Dipper Urine Dipstick Control is designed for use with most urinalysis reagent strips. It can also be used for confirmatory tests and refractometry.
- Comprehensive and cost-effective
- Lyophilized, human serum-based
- 3-year shelf life from date of manufacture
- 7-day reconstituted stability when stored at 2 – 8º C*
Total Lipids Control is a comprehensive lipid control – it monitors the performance of major lipids, lipoproteins and apolipoprotein assay methods. Designed for use with most major chemistry analyzers including AU® Series, Dimension,® Hitachi,®Synchron® and Vitros.® We provide HDL values for direct HDL methods and HDL precipitation methods: Dextran Sulfate 50,000 MW. Apolipoprotein A-1 and B values are established using an IFCC standardized immunoturbidimetric method.
Ammonia/Alcohol
Control
- 2-year refrigerated shelf life from date of manufacture
- 4-month open vial stability when stored at 2 – 8º C*
- Liquid, ready-to-use
- Three levels
With Ammonia/Alcohol Control, monitor the performance of ammonia and ethanol assay methods at three clinically significant levels. Our Ammonia/Alcohol Control is perfect for use with most major chemistry analyzers including Cobas,® Dimension,® EMIT,® Hitachi,® Synchron® and Vitros.®
Dropper® A1c
Diabetes Control
- Extended stability
- Easy-to-use dropper bottles
- Liquid, human blood based
Use Dropper A1c for laboratory and point-of-care hemoglobin A1c quality control. Features three years frozen (from date of manufacture) and six months of ?refrigerated open vial stability for reduced waste – plus dropper bottles for easy dispensing. Twenty one days of open vial room temperature stability eliminates storage problems and provides maximum portability – perfect for sites without refrigeration. Designed for use with most major immunoassay and boronate affinity laboratory and POCT analyzers including Siemens® DCA 2000/2000+/Vantage™ and Siemens Dimension, Beckman Coulter® Synchron,® Roche® Cobas Integra®, Roche Hitachi, Ortho-Clinical Diagnostics® Vitros,® Primus Diagnostics PDQ/ultra2.
QuanTtest® Red
Total Protein Assay System Kit
- For quantitative determination of protein in cerebrospinal fluid and urine for both manual and automated systems
- Reagents stable until the expiration date when stored properly*
- Standards and Controls are stable until the expiration date when stored at 2 – 8º C*
Pyrogallol Red Molybdate dye binding method provides a simple, ready-to-use colorimetric method for total protein quantitation with greater linearity, using microliter samples of urine or cerebrospinal fluid (CSF) in manual or automated systems.
The kit consists of reagent, controls for both CSF and urine chemistry, and four reagent standards: level 2 (25 mg/dL), level 3 (50 mg/dL), level 4 (100 mg/dL), and level 5 (200 mg/dL).
Reagent and Protien Standards also sold separately.
Blood Collection from Globe Scientific–Transfer Pipettes, Caps and Capillary Tubes
All of Globe Scientific’s blood collection products are precision crafted to insure maximum safety during blood collection procedures. The Cappers™ line of tube caps provides a tight fit for a wide variety of blood collection tubes while our plastic capillary tubes and disposable needle holder offer phlebotomists a safer method for drawing and handling blood samples.
Globe Scientific Inc.–Caps for Blood Collection Tubes, Micro-Hematocrit Capillary Tubes – GLASS, Micro-Hematocrit Capillary Tubes – PLASTIC, & Needle Holder, Disposable.
Globe Scientific, Inc.–Transfer Pipettes, Transfer Pipettes Brochure
Highest Quality Rapid Diagnostic Test Kits from Scimedx and Medion Diagnostics.
Medion Diagnostics ELISA –Thyroid, Thrombosis, Rheumatology, Syphilis, Infectious, Mononucleosis, Early Childhood Diseases (Measels, Mumps, Varicella), Torch
Medion Diagnostics IFA–Infectious Disease Assays, Slide Packs, Conjugates (prediluted with Eriochrome Black counterstain), ELISA 96 Test KITS Infectious, ELISA 96 Test, KITS Autoimmune, Latex Assays, & Serology Assays
Scimedx IFA–Viral & Infections IFA Kits, Slides, DipStick Tests, & Latex Agglutination Assays.
Pro-Lab Diagnostics – ProLex™ Streptococcal Grouping Latex Kits and Individual Grouping Reagents
Complete kits or individual grouping reagents for the identification of Lancefield Groups A, B, C, D, F & G. Pro-Lab Diagnostics also offers custom grouping kits from any of the six grouping latex.
Catachem Inc.’s VetSpec™ Ethylene Glycol Qualitative Reagent Test Kit
For IN VITRO diagnostic use in the Qualitative determination of Ethylene Glycol in serum or plasma in the Veterinary Laboratory.
When Ethyl Glycol is ingested in the form of antifreeze or other automotive products, Ethylene Glycol results in central nervous system depression, cardiopulmonary compromise, and renal insufficiency. Laboratory features of Ethylene Glycol poisoning include increase anion gap, and increased osmolal gap, calcium oxalate crystaluria, and detectable Ethylene Glycol in serum.